Also known as the Tei index. It is an index that incorporates both systolic and diastolic time intervals in expressing global systolic and diastolic ventricular function. Systolic dysfunction prolongs prejection (isovolumic contraction time, IVCT) and a shortening of the ejection time (ET). Both systolic and diastolic dysfunction result in abnormality in myocardial relaxation which prolongs the relaxation period (isovolumic relaxation time, IVRT).
LV MPI =
IVCT + IVRT
LVET
=
MCOT - LVET
LVET
Variable
Definition
Input
MCOT
Mitral Valve Closure to Opening Time (ms)
LVET
LV Ejection time (ms)
Output
LV MPI
LV Myocardial Performance Index
Normal
0.39 ±0.05
Dilated cardiomyopathy
0.59 ±0.10
References
Tei C, Ling LH, Hodge DO, et al. New index of combined systolic and diastolic myocardial performance: a simple and reproducible measure of cardiac function - a study in normals and dilated cardiomyopathy. J Cardiol 1995;26:357-366.
Oh JK et al. The Echo Manual. 2nd ed. p. 55, 1999.