The LV contractility dP/dt can be estimated by using time interval between 1 and 3m/sec on MR velocity CW spectrum during isovolumetric contraction i.e. before aortic valve opens when there is no significant change in LA pressure.
dP/dt =
32
T
Variable
Definition
T
Time (1 to 3 m/sec MR) (seconds, s)
dP/dt
dP/dt (mmHg/s)
Normal
≥1200 mmHg/s
References
Bargiggia GS, et al. A. new method for estimating left ventricular dP/dt by continuous wave Doppler echocardiography: Validation studies at cardiac catheterization. Circulation 1989; 80: 1287-1292.
Chung N, et al. Measurement of left ventricular dp/dt by simultaneous Doppler echocardiography and cardiac catheterization. J Am Soc Echocardiogr 1992; 5:147-152.