Aortic valve area can be calculated by using the principle of conservation of mass — "What comes in must go out".
Aortic valve area indexed to body surface area should be considered for the large and small extremes of body surface area.
For patients with prosthetic aortic valves, patient-prosthesis mismatch is suspected when effective orifice area (EOA) indexed to body surface area <0.85 to 0.9 cm2/m2. Patient-prosthesis mismatch is considered severe when EOA index <0.65.
EOA Index (cm2/m2)
Subvalvular velocity time integral (cm)
Maximum velocity time integral across the valve (cm)
Left ventricular outflow tract diameter (cm)
Weight (kg or lb)
Height (cm or in)
Aortic Valve Area (cm2)
Aortic Valve Area indexed to BSA (cm2/m2)
Baumgartner H, et al. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr. 2009 Jan;22(1):8,10.
Zoghbi WA, et al. Accurate noninvasive quantification of stenotic aortic valve area by Doppler echocardiography. Circulation 1986; 73:452-459.
Grayburn PA, et al. Pivotal role of aortic valve area calculation by the continuity equation for Doppler assessment of aortic stenosis in patients with combined aortic stenosis and regurgitation. Am J. Cardiol 1988; 61:376-381.
Carabello BA, et al. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease. Circulation 2006; 114(5):e84-231.
Pibarot P, Dumesnil JG. Hemodynamic and clinical impact of prosthesis-patient mismatch in the aortic valve position and its prevention. J Am Coll Cardiol 2000;36:1131-41.
Jamieson E. et al. Surgical Management of Valvular Heart Disease 2004. Canadian Cadiovascular Society Consensus Conference. Can J Cardio Vol 2004; 20 Suppl E:18E-19E.
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